Complete genome sequence of new unique recombinant HIV type 1 isolated from a child born to an HIV-infected mother
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منابع مشابه
Cloning, Expression, Purification and Immunoreactivity Analysis of Gag Derived Protein p17 from HIV-1 CRF35 in Fusion with Thioredoxin from Human Subjects
So far, recombinant antigens of HIV-1, the etiologic cause of Acquired Immunodeficiency Syndrome (AIDS), have been widely used for the diagnosis and vaccine development. P17 or the matrix protein formed by the proteolytic cleavage of gag is strongly antigenic and is as conserved and immunogenic as p24. In some cases, antibodies to p17 are more prevalent than antibodies to p24 and the decline in...
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Background There are contradictory results regarding association between maternal HIV infection and neonatal adverse outcomes. Therefore, in this study the neonates born from HIV-positive mothers compared with HIV-negative mothers were assessed in Tehran, Iran.<b...
متن کاملHLA-G DNA sequence variants and risk of perinatal HIV-1 transmission
BACKGROUND HLA-G gene is a non-classical MHC class 1 molecule that is highly expressed in the trophoblast at the maternal-fetal interface. In an attempt to elucidate possible immunological mechanisms facilitating protection of infants born to human immunodeficiency virus type (HIV-1) infected mothers, we have been studying genetic variations in the coding and untranslated regions of HLA-G antig...
متن کاملChallenges and Proposed Actions for HIV/AIDS Control among Children in Iran
It is estimated globally 3.2 million children were living with HIV in 2014, that mostly in sub-Saharan Africa. However, the majority of them infected to HIV from their mothers during pregnancy, during delivery or breastfeeding (1). Antiretroviral therapy (ART) use during and after pregnancy is essential for prevention of mother-to-child transmission (PMTCT) of HIV (2). In the absence of any in...
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BACKGROUND In 2000, Thailand implemented a national program to prevent mother-to-child HIV transmission (PMTCT). OBJECTIVE To describe the effectiveness of the prevention of mother-to-child HIV transmission program in Thailand. DESIGN AND METHODS A register of HIV-exposed children at birth was created with follow-up of infection status. The register included children born to HIV-infected wo...
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